Depression is one of the most common diagnoses encountered in primary care practice. It is often difficult to obtain a prompt mental health referral, and the management of depression often becomes a primary care activity. In this lecture, we will discuss screening for depression, and the rational selection of antidepressant medication based on side effect profiles, with a focus on effects on sleep and weight. We will also discuss optimal strategies for dual antidepressant augmentation treatment.

Learning Objectives:

  • Develop an approach to screening for depression in primary care
  • Select antidepressants based on their side effect profiles, including their effects on weight and sleep
  • Use combination therapy optimally to augment antidepressant response